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题目:警告:一种新的致死性的大肠杆菌在英国传播
摘要:摘自 foodhaccp.com
A NEW killer strain of the E.coli bug from continental Europe
could soon be posing a serious public health threat in Britain,
experts fear. The bacterium, Escherichia coli 026, is just
as dangerous as the notorious 0157 version that can cause
fatal food poisoning in children and the elderly - but it
can slip through the standard test used to pick out 0157 from
other bacteria. In November 1996, E.coli 0157 killed at least
20 elderly people in Wishaw, Lanarkshire, and made another
500 seriously ill after they ate contaminated meat products
from John Barr butcher shop in the town. The incident -
Britain worst 0157 outbreak - led to a report containing
32 safety recommendations and an E.coli taskforce was set
up by the Scottish Executive. A recent outbreak of E.coli
026 in Scotland, and findings from a study looking at cattle
infection, alerted researchers to the potential new problem.
Dr Mark Stevens, from the Institute for Animal Health, said:
"026 appears to be much more prevalent in the UK than
we previously thought. The likelihood is these bugs are going
to enter the human food chain more often in the future. "E.coli
026 is here and we should be aware of it. The indications
are that we cannot limit our sights only to 0157." Like
other E.coli strains, 026 makes its home in the gut of cattle.
It can spread to humans via faecal contamination of meat at
slaughterhouses, and is a particular risk in undercooked hamburgers.
Children playing on farms run the risk of picking up the bug
by getting their hands dirty and not washing them. A survey
last year showed that about 5 per cent of UK cattle carried
E.coli 0157. Almost a half of all herds had at least one animal
infected with the bacterium. Dr Stevens, who is developing
a cattle vaccine against E.coli, will present new findings
at a meeting of the Society for General Microbiology in Manchester
today. He said earlier this year that four people from Scotland
were found to have been infected by E.coli 026 bacteria. A
fifth had acquired a rarer strain called 0113. The patients
were from the Ayrshire and Arran health board area, the Forth
Valley region, Lothian and Tayside. A team led by Professor
Gad Frankel, from Imperial College London, recently reported
the new cattle study in the journal Letters of Applied Microbiology.
The scientists detected 132 suspect E.coli 026 isolates in
745 samples of cattle faeces from a single Scottish farm.
Of these, 85 per cent were confirmed as being the 026 strain.
Dr Stevens said 026 was already well known in continental
Europe, and proving a particular problem in Germany. But up
to now there had been little sign of it in the UK. "For
reasons we don抰 really understand, different types of this
class of E.coli are prevalent in different countries,"
he said. "The one you mostly have in North America and
the UK is 0157." Although sophisticated antibody techniques
can detect 026, it cannot be identified with the simple culture
test normally used to spot 0157. There is a danger, therefore,
that 026 might be allowed to spread unseen. However, Dr Stevens?team
has made significant progress towards an effective answer
to all kinds of E.coli. The group has identified 60 genes
needed by the bug to survive in cattle intestines. Dr Stevens,
who will outline the results at today meeting at the University
of Manchester Institute of Science and Technology, said the
scientists were looking at ways of using the new information
to combat the bacteria. They had developed a vaccine designed
to trigger an immune response against a particular E.coli
protein, he said. It is hoped the vaccine will kill the bacteria
in the living cow and make it far harder to pass to humans.
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